USS Barbel (SS-316), a Balao-class submarine, was the first ship of the United States Navy to be named for the barbel, a cyprinoid fish, commonly called a minnow or carp.

Barbel keel was laid down by the Electric Boat Company of Groton, Connecticut. She was launched on 14 November 1943 sponsored by Mrs. Harold A. Allen, and commissioned 3 April 1944, Commander R. A. Keating in command.

Barbel arrived at Pearl Harbor on 21 June 1944 and commenced preparation for her first war patrol. From 15 July 1944-4 February 1945, she carried out four war patrols and is officially credited with sinking six Japanese ships totaling 15,263 tons.

Barbel departed Fremantle, Australia, on 5 January 1945 for theSouth China Sea on her fourth patrol. Late in January she was ordered to form a "wolfpack" with Perch and Gabilan and patrol the western approaches to Balabac Strait and the southern entrance toPalawan Passage. On 3 February, Barbel sent a message reporting that she had been attacked three times by enemy aircraft droppingdepth charges and would transmit further information on the following night.

Barbel was never heard from again. Japanese aviators reported an attack on a submarine off southwest Palawan on 4 February. Two bombs were dropped and one landed on the submarine near the bridge. The sub plunged, under a cloud of fire and spray. This was very likely the last engagement of Barbel. She was officially reported lost on 16 February 1945.